Learning Objectives/Outcomes • Old drugs, new uses: introduction to repurposed drugs • Scientific foundation and rationale to opt for a drug development strategy with focus on repurposed versus new molecules to treat age-associated diseases such as sarcopenia and osteoporosis • Diverse discovery strategies to identify novel safe and effective treatments for age-associated diseases through repositioning of old molecules • Trajectories and timelines for clinical drug development of repurposed versus new molecules, with different challenges and opportunities • The potential of combination therapy for the development of new drugs in age-associated diseases • Examples of repurposed molecules considered to treat sarcopenia and osteoporosis