Between 20,000 and 50,000 Americans have OI, which causes brittle bones to break easily because of a problem with collagen production.
Osteoporosis is a major public health threat for 44 million Americans. Of the 10 million who have osteoporosis, 80 percent are women.
Bone metastasis occurs in up to 80 percent of patients with myeloma, and 70 percent of patients with breast or prostate cancer.
Bone research is under-funded in relation to the economic burden of bone-related diseases.