• Systems Biology Approaches to Skeletal Disease

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    Systems Biology Approaches to Skeletal Disease

    Course Overview

    Sponsored by the American Society for Bone and Mineral Research

    Learning Objectives

    1. Understand the current status of using systems biology approaches to study bone health and disease.
    2. Appreciate that not all bones are constructed in the same way and that there are clinically important inter-individual differences in bone structure and function.
    3. Appreciate that individuals may arrive at a fracture state through different biomechanical pathways.

    Presenter Information

    Karl Jepsen, Ph.D.

    Dr. Karl Jepsen is Professor and Associate Chair of Research for the Department of Orthopaedic Surgery at the University of Michigan. His background is in Bioengineering. Dr. Jepsen's research group focuses on understanding how complex physiological systems such as bone establish function during growth and maintain function during aging. Developing a better understanding of how complex systems work is expected to benefit efforts to reduce fracture risk by identifying the genetic and environmental factors that impair (or promote) specific components of the functional adaptation process that compromise (or improve) musculoskeletal health.


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