• TGF-b & Bone Remodeling

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    TGF-b & Bone Remodeling

    Course Overview

    Sponsored by the American Society for Bone and Mineral Research

    Learning Objectives

    1. Mechanisms of Bone Remodeling
    2. The Function of TGF-b1 in Bone Remodeling
    3. The Role of Skeletal Stem Cell during Bone Remodeling

    Presenter Information

    Xu Cao, Ph.D.

    Xu Cao, Ph.D., is currently Lee Riley professor and co-director, Center for Musculoskeletal Research Department of Orthopedic Surgery at Johns Hopkins University. His primary research interest is focusing on the coupling mechanism of bone resorption and bone formation during bone remodeling. His group has identified that active TGF-b1 released during osteoclastic bone resorption induces migration of bone mesenchymal stem cells to couple bone resorption with formation. He did 5 years of postdoct training at Washington University in Dr. Steve Teitelbaum's lab. In 1996, he took an assistant professor position at University of Alabama at Birmingham and became full professor in 2004.


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