This study examined whether intakes of different dietary fats are associated with alterations of serum 25-hydroxyvitamin D (25OHD) after supplementation with vitamin D(3). 152 healthy men and women age 65 and older were assigned to receive 700 IU/day of vitamin D(3) and 500 mg/d calcium. Intakes of monounsaturated fatty acids (MUFA), polyunsaturated fatty acids (PUFA), and saturated fatty acids (SFA) were estimated by food frequency questionnaire and changes in plasma 25OHD over 2 years assessed. The authors found that changes in plasma 25OHD during vitamin D supplementation was positively associated with MUFA, and negatively associated with PUFA.
Niramitmahapanya S, Harris SS, Dawson-Hughes B.