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    Langerhans cells down-regulate inflammation-driven alveolar bone loss.

    The role of Langerhans cells in the bone resorption that is associated with chronic infections and inflammatory diseases is unclear.  These authors used a model involving inflammation-driven alveolar bone loss caused by to infection to show that in vivo ablation of Langerhans cells produced enhanced bone loss.

    http://www.ncbi.nlm.nih.gov/pubmed/22509018

    Arizon M, Nudel I, Segev H, Mizraji G, Elnekave M, Furmanov K, et al