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    Down-Regulation of miR-21 biogenesis by estrogen action contributes to osteoclastic apoptosis

    The authors demonstrate that the proapoptotic effect of estrogen during osteoclastogenesis is regulated by a posttranscriptional increase in FasL production by down-regulated microRNA-21 (miR-21) biogenesis. 

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    Sugatani T, Hruska KA.