The June 2011 issue of the Journal for Bone and Mineral Research (JBMR) is now off press. Highlights in this issue include:

• Perspective: Genome-scale techniques highlight the epigenome and redefine fundamental principles of gene regulation
• Commentary: Osteoinductive signals and heterotopic ossification
• Original article: Hyperlipidemia induces resistance to PTH bone anabolism in mice via oxidized lipids

The online version is available on the JBMR Website.