In vivo experiments with strontium HA nanoparticles loaded-implants.

* Giulia Montagna, Molecular Medicine Department (DMM), Center for Health Technologies (CHT), UdR INSTM, University of Pavia, Viale Taramelli 3/B - 27100 Pavia – ITALY, Beth Bragon, Department of Orthopaedic Surgery, Boston University School of Medicine, 72 East Concord St, Evans 243, Boston, MA, 02118, USA. , Paola Divieti Pajevic, Molecular and Cell Biology, Boston University Henry M. Goldman School of Dental Medicine, Boston MA, Livia Visai, Molecular Medicine Department (DMM), Center for Health Technologies (CHT), UdR INSTM, University of Pavia, Viale Taramelli 3/B - 27100 Pavia – ITALY, Louis Gerstenfeld, Department of Orthopaedic Surgery, Boston University School of Medicine, Boston, MA 02118, USA. Electronic address: bragdon@bu.edu.
Poster Sessions, Presentation Number: SUN-794
Session: Poster Session II
Sunday, September 22, 2019 12:30 PM - 2:30 PM, Orange County Convention Center , West Hall C

SMAD3 Somatic Activating Mutations Cause Melorheostosis with an Endosteal Radiographic Pattern by Upregulating the TGF-β/SMAD Pathway

* Heeseog Kang, Section on Heritable Disorders of Bone and Extracellular Matrix, NICHD, NIH, Aleksandra Ivovic, Immunoregulation Section, Autoimmunity Branch, NIAMS, NIH, Smita Jha, Section on Congenital Disorders, Clinical Center, NIH, Nadja Fratzl-Zelman, Ludwig Boltzmann Institute of Osteology at the Hanusch Hospital of WGKK and AUVA Trauma Centre Meidling, 1st Medical Department Hanusch Hospital, Zuoming Deng, Biodata Mining and Discovery Section, Office of Science and Technology, NIAMS, NIH, Apratim Mitra, Bioinformatics and Scientific Programming Core, NICHD, NIH, Wayne A. Cabral, Section on Heritable Disorders of Bone and Extracellular Matrix, NICHD, NIH, Eric P. Hanson, Immunodeficiency and Inflammation Unit, Autoimmunity Branch, NIAMS, NIH, Eileen Lange, Office of the Clinical Director, NIAMS, NIH, James Katz, Office of the Clinical Director, NIAMS, NIH, Paul Roschger, Ludwig Boltzmann Institute of Osteology at the Hanusch Hospital of WGKK, and AUVA Trauma Center Meidling, 1st Medical Department Hanusch Hospital, Klaus Klaushofer, Ludwig Boltzmann Institute of Osteology at the Hanusch Hospital of WGKK, and AUVA Trauma Center Meidling, 1st Medical Department Hanusch Hospital, Ryan K. Dale, Bioinformatics and Scientific Programming Core, NICHD, NIH, Richard M. Siegel, Immunoregulation Section, Autoimmunity Branch, NIAMS, NIH, Timothy Bhattacharryya, Clinical and Investigative Orthopedics Surgery Unit, NIAMS, NIH, Joan C. Marini, Section on Heritable Disorders of Bone and Extracellular Matrix, NICHD, NIH
Oral Presentations, Presentation Number: 1134
Session: Plenary Orals: Rare Bone Diseases: Translational Studies
Monday, September 23, 2019 8:00 AM - 8:15 AM, Orange County Convention Center , Valencia Ballroom A

The Slow and Sustained Release of a Low Dose of BMP-7 Accelerates Implant Healing in an Osteoporotic Environment

* Ernst B Hunziker, Bern University Hospital, Departement of Osteoporosis, Nahoko Shintani, Bern University Hospital, Dept. Osteoporosis, Kurt Lippuner, Bern University Hospital, Dept. Osteoporosis
Poster Sessions, Presentation Number: SUN-789
Session: Poster Session II
Sunday, September 22, 2019 12:30 PM - 2:30 PM, Orange County Convention Center , West Hall C

De novo missense mutation in SP7 in a patient with cranial hyperostosis, long bone fragility, and increased osteoblast number

* Julian Lui, Section on Growth and Development, NICHD, Adalbert Raimann , Department of Paediatrics and Adolescent Medicine, Medical University of Vienna, Lijin Dong, Genetic Engineering Core, NEI, Hironori Hojo , Center for Disease Biology and Integrative Medicine, The University of Tokyo, Paul Roschger, Ludwig Boltzmann Institute of Osteology at the Hanusch Hospital of WGKK and AUVA Trauma Centre, Hanusch Hospital , Nadja Fratzl-Zelman, Ludwig Boltzmann Institute of Osteology at the Hanusch Hospital of WGKK and AUVA Trauma Centre, Hanusch Hospital , Youn Hee Jee, Section on Growth and Development, NICHD, Gabriele Haeusler, Department of Paediatrics and Adolescent Medicine, Medical University of Vienna, Jeffrey Baron, Section on Growth and Development, NICHD
Poster Sessions, Presentation Number: LB SUN-1083
Session: Late-Breaking Posters II
Sunday, September 22, 2019 12:30 PM - 2:30 PM, Orange County Convention Center , West Hall C

Direct Interactions between Multiple Myeloma Cells and Osteocytes in the Hypoxic Myeloma Microenvironment Induce a Pro-angiogenic Phenotype in Osteocytes

* Patrick L. Mulcrone, Indiana University School of Medicine, Daniela N. Petrusca, Indiana University School of Medicine, Keith W. Condon, Indiana University School of Medicine, Jesús Delgado-Calle, Indiana University School of Medicine, G. David Roodman, Indiana University School of Medicine
Poster Sessions, Presentation Number: SUN-573
Session: Poster Session II
Sunday, September 22, 2019 12:30 PM - 2:30 PM, Orange County Convention Center , West Hall C

Eif2ak4/GCN2 maintains bone homeostasis through regulation of skeletal stem cell proliferation

* Guoli Hu, Department of Orthopaedic Surgery, Duke University School of Medicine, Yilin Yu, Department of Orthopaedic Surgery, Duke University School of Medicine, Fanxin Long, Department of Orthopaedic Surgery, University of Pennsylvania, Courtney Karner, Department of Orthopaedic Surgery, Duke University School of Medicine
Poster Sessions, Presentation Number: FRI-386
Session: Welcome Reception and Plenary Poster Session
Friday, September 20, 2019 5:30 PM - 7:00 PM, Orange County Convention Center , West Hall C
Poster Sessions, Presentation Number: SAT-386
Session: Poster Session I
Saturday, September 21, 2019 12:30 PM - 2:30 PM, Orange County Convention Center , West Hall C

Fip200, an Essential Autophagy Gene, Mediates the Anabolic Action of PTH in Bone

* Shuqun Qi, University of Michigan School of Dentistry, Li Wang, University of Michigan School of Dentistry, Han Kyoung Choi, University of Michigan School of Dentistry, Jian Pan, West China College of Stomatology, Sichuan University, Jun-Lin Guan, University of Cincinnati College of Medicine, Laurie McCauley, University of Michigan School of Dentistry, Fei Liu, University of Michigan School of Dentistry
Oral Presentations, Presentation Number: 1064
Session: Concurrent Orals: Osteoblasts
Saturday, September 21, 2019 4:30 PM - 4:45 PM, Orange County Convention Center , W315

Multiple Modalities of Signaling by FOP Mutant BMP Receptor in the Developing Zebrafish

* Robyn Allen, University of Pennsylvania School of Medicine, Eileen Shore, University of Pennsylvania School of Medicine, Mary Mullins, University of Pennsylvania School of Medicine
Poster Sessions, Presentation Number: FRI-916
Session: Welcome Reception and Plenary Poster Session
Friday, September 20, 2019 5:30 PM - 7:00 PM, Orange County Convention Center , West Hall C
Poster Sessions, Presentation Number: SAT-916
Session: Poster Session I
Saturday, September 21, 2019 12:30 PM - 2:30 PM, Orange County Convention Center , West Hall C

O-glycosylation a Novel Post-Translational Modification of Osteocalcin Increases its Half-life In Vivo

* Omar Al Rifai, Institut de Recherches Cliniques de Montréal, Catherine Julien, Institut de Recherches Cliniques de Montréal, Denis Faubert, Institut de Recherches Cliniques de Montréal, Yoshiki Narimatsu, Department of Cellular and Molecular Medicine, Copenhagen Center for Glycomics and University of Copenhagen, Henrik Clausen, Department of Cellular and Molecular Medicine, Copenhagen Center for Glycomics and University of Copenhagen, Mathieu Ferron, Institut de Recherches Cliniques de Montréal
Poster Sessions, Presentation Number: SUN-225
Session: Poster Session II
Sunday, September 22, 2019 12:30 PM - 2:30 PM, Orange County Convention Center , West Hall C

Rmrp mutation disrupts chondrogenesis and bone ossification in zebrafish model of cartilage-hair hypoplasia via enhanced Wnt/β-catenin signaling

* Xianding Sun, Laboratory for the Rehabilitation of Traumatic Injuries, State Key Laboratory of Trauma, Burns and Combined Injury, Trauma Center, Research Institute of Surgery, Daping Hospital, Army Medical University, Yangli Xie, Laboratory for the Rehabilitation of Traumatic Injuries, State Key Laboratory of Trauma, Burns and Combined Injury, Trauma Center, Research Institute of Surgery, Daping Hospital, Army Medical University, Lin Chen, Laboratory for the Rehabilitation of Traumatic Injuries, State Key Laboratory of Trauma, Burns and Combined Injury, Trauma Center, Research Institute of Surgery, Daping Hospital, Army Medical University
Poster Sessions, Presentation Number: LB MON-1087
Session: Late-Breaking Posters III
Monday, September 23, 2019 12:00 PM - 2:00 PM, Orange County Convention Center , West Hall C